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Cytokinetics, Incorporated (CYTK) Stock Fundamentals, Analysis & Risk Signals

Health score, competitive moat, risk signals, and key metrics at a glance.

NasdaqGS•Healthcare•Biotechnology
D
WeakMetricSide Score: 27/100
ProfitabilityProfit0/30
GrowthGrowth15/25
Balance SheetBalance10/25
Cash QualityCash2/20
Price & Volume
Market Cap $10.66M

Cytokinetics, Incorporated, a biopharmaceutical company, focuses on discovering, developing, and commercializing novel muscle activators and muscle inhibitors as potential treatments for debilitating diseases in the United States. The company markets MYQORZO, a novel, oral, and small molecule cardiac myosin inhibitor for the treatment of symptomatic oHCM. It also develops Aficamten, a novel, oral, and small molecule cardiac myosin inhibitor for the treatment of HCM; and omecamtiv mecarbil, a potential treatment across the continuum of care in heart failure with severely reduced ejection fraction. In addition, the company is involved in developing and Ulacamten, a novel, selective, oral, and small molecule cardiac myosin inhibitor designed to reduce the hypercontractility associated with heart failure with preserved ejection fraction in Phase 1 clinical trials; and CK-089, a fast skeletal muscle troponin activator in Phase 1 clinical trials. Cytokinetics, Incorporated was incorporated in 1997 and is headquartered in South San Francisco, California.

Moat Signals

Competitive analysis based on 60 quarters of fundamental data

Pricing Power

Weak Moat

Operating margins are under pressure, averaging -13012.5%. The business may lack pricing power or face rising costs.'

Competitive Advantage

Moderate Moat

Limited ROE data for a reliable assessment.

Cash Generation

Weak Moat

Only 0 of the last 8 quarters had positive FCF — the business may require external capital to sustain operations.

Demand Durability

Strong Moat

TTM revenue has grown consistently (7 of 7 quarters up), with ~3276.4% growth over the period. Strong demand durability.

Risk Signals

Data-driven red flags and warnings across 60 quarters

High Risk

Margin Pressure

Red Flag

The company posted negative operating margins in recent quarters — core operations are unprofitable.

Earnings Quality

Red Flag

Free cash flow has been negative in 8 of the last 8 quarters — earnings are not translating to cash.

Leverage Risk

Healthy

Limited debt-to-equity data available.

Revenue Decline

Healthy

Revenue is stable or growing over recent quarters — demand appears durable.

Cash Burn

Red Flag

The last 8 consecutive quarters had negative FCF — the company is burning cash and may need external funding.

Share Dilution

Red Flag

Shares outstanding increased 12.8% — significant dilution, likely from stock compensation or capital raises.

Metrics at a Glance

as of March 2026

Revenue & Profit

Revenue, EBITDA, operating income, net income, EPS, and shares

TTM Revenue
$105.81M
450.6%
Q. Revenue
$19.36M
TTM EBITDA
$-624.08M
13.2%
TTM Op. Income
$-640.25M
13.2%
Q. Op. Income
$-183.62M
TTM Net Income
$-829.61M
34.8%
Q. Net Income
$-206.03M
EPS
$-1.67
Shares Out.
$123,273
4.0%
$105.81M in TTM revenue grew 450.6% YoY, reaching $19.36M last quarter. TTM EBITDA of $-624.08M and TTM operating income of $-640.25M shows growth is flowing through. However, net income is negative at $829.61M — growth is not yet reaching the bottom line. Revenue is growing at a healthy pace — a signal to hold.

Margins

Gross, EBITDA, operating, and net margin trends

Gross Margin
99.2%
EBITDA Margin
-931.2%
Op. Margin
-948.7%
90.4%
Net Margin
-1064.5%
89.6%
Op. margin of -948.7% is up 8907.6% YoY — cost efficiency is improving. Net margin at -1064.5% and gross margin of 99.2% — earnings take a bigger bite when COGS stays lean..

Price Ratios

P/E, P/S, P/B, EV/EBITDA, FCF yield, and earnings yield

P/E Ratio
N/A
P/S Ratio
0.1x
P/B Ratio
N/A
P/S of 0.1x and P/B of 0.0x. A low P/S may indicate the stock is undervalued.

Assets & Liabilities

Total assets, cash, debt, book value, and leverage

Total Assets
$1.27B
Cash
$129.84M
Long-Term Debt
$247.21M
Book Value
$-826.57M
D/E Ratio
N/A
Debt/EBITDA
N/A

Cash Flow

Operating cash flow, free cash flow, FCF margin, and earnings quality

Op. Cash Flow
$-145.46M
Free Cash Flow
$-151.39M
10.3%
FCF Margin
-143.1%
FCF / Net Income
0.7
FCF of $-151.39M on $-145.46M in operating cash flow. The FCF / Net Income ratio of 0.2x indicates partial cash conversion — earnings quality needs attention.

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