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GRAIL (GRAL) Stock Fundamentals, Analysis & Risk Signals

Health score, competitive moat, risk signals, and key metrics at a glance.

NasdaqGS•Healthcare•Diagnostics & Research
D
WeakMetricSide Score: 30/100
ProfitabilityProfit0/30
GrowthGrowth15/25
Balance SheetBalance13/25
Cash QualityCash2/20
Price & Volume
Market Cap $2.97B

GRAIL, Inc., a commercial-stage healthcare company, provides multi-cancer early detection testing and services in the United States and internationally. It offers Galleri, a cancer screening test for asymptomatic individuals over 50 years of age; and a diagnostic aid for cancer tests to accelerate diagnostic resolution for patients with clinical suspicion of cancer. The company also provides development services, including support for ongoing clinical studies, pilot testing, research, and therapy development. In addition, its precision oncology portfolio consists of n RUO-targeted methylation-based platform that enables applications for disease prognostication, risk stratification, minimal residual disease detection, and recurrence and relapse monitoring. The company was incorporated in 2015 and is headquartered in Menlo Park, California.

Moat Signals

Competitive analysis based on 8 quarters of fundamental data

Pricing Power

Weak Moat

Operating margins are under pressure, averaging -1028.6%. The business may lack pricing power or face rising costs.'

Competitive Advantage

Weak Moat

ROE is low or negative, suggesting limited competitive advantage or capital allocation challenges.

Risk Signals

Data-driven red flags and warnings across 8 quarters

High Risk

Margin Pressure

Red Flag

The company posted negative operating margins in recent quarters — core operations are unprofitable.

Earnings Quality

Red Flag

Free cash flow has been negative in 8 of the last 8 quarters — earnings are not translating to cash.

Leverage Risk

Healthy

Limited debt-to-equity data available.

Revenue Decline

Healthy

Revenue is stable or growing over recent quarters — demand appears durable.

Cash Burn

Red Flag

The last 8 consecutive quarters had negative FCF — the company is burning cash and may need external funding.

Share Dilution

Red Flag

Shares outstanding increased 30.9% — significant dilution, likely from stock compensation or capital raises.

Metrics at a Glance

as of March 2026

Revenue & Profit

Revenue, EBITDA, operating income, net income, EPS, and shares

TTM Revenue
$156.12M
0.8%
Q. Revenue
$40.78M
TTM EBITDA
$-394.02M
81.5%
TTM Op. Income
$-544.32M
76.8%
Q. Op. Income
$-135.76M
TTM Net Income
$-395.32M
81.5%
Q. Net Income
$-93.19M
EPS
$-2.29
Shares Out.
$40.64M
18.5%
$156.12M in TTM revenue declined 0.8% YoY, reaching $40.78M last quarter. TTM EBITDA of $-394.02M and TTM operating income of $-544.32M shows growth is flowing through. However, net income is negative at $395.32M — growth is not yet reaching the bottom line. Revenue is contracting — assess whether this is cyclical or structural.

Margins

Gross, EBITDA, operating, and net margin trends

EBITDA Margin
-240.5%
Op. Margin
-332.9%
31.0%
Net Margin
-228.5%
31.5%
Op. margin of -332.9% is up 149.6% YoY — cost efficiency is improving. Net margin at -228.5%.

Price Ratios

P/E, P/S, P/B, EV/EBITDA, FCF yield, and earnings yield

P/E Ratio
N/A
P/S Ratio
19.1x
P/B Ratio
1.2x
P/S of 19.1x and P/B of 1.2x. A high P/S suggests growth expectations are priced in.

Assets & Liabilities

Total assets, cash, debt, book value, and leverage

Total Assets
$2.80B
Cash
$69.34M
Long-Term Debt
N/A
Book Value
$2.50B
D/E Ratio
N/A
Debt/EBITDA
N/A

Cash Flow

Operating cash flow, free cash flow, FCF margin, and earnings quality

Op. Cash Flow
$-86.99M
TTM Free Cash Flow
$-292.33M
56.8%
FCF Margin
-187.2%
FCF / Net Income
0.7
TTM FCF of $-292.33M on $-86.99M in operating cash flow. The FCF / Net Income ratio of 0.7x means earnings are well backed by actual cash — high-quality earnings.

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Cash Generation

Weak Moat

Only 0 of the last 8 quarters had positive FCF — the business may require external capital to sustain operations.

Demand Durability

Weak Moat

Revenue has been flat or declining over recent quarters, which may indicate eroding demand or competitive pressure.