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Jazz Pharmaceuticals (JAZZ) Stock Fundamentals, Analysis & Risk Signals

Health score, competitive moat, risk signals, and key metrics at a glance.

NasdaqGS•Healthcare•Biotechnology
B
GoodMetricSide Score: 66/100
ProfitabilityProfit23/30
GrowthGrowth9/25
Balance SheetBalance19/25
Cash QualityCash15/20
Price & Volume
Market Cap $15.07B

Jazz Pharmaceuticals plc identifies, develops, and commercializes pharmaceutical products in the United States, Europe, and internationally. The company offers Xywav to treat cataplexy or excessive daytime sleepiness (EDS) with narcolepsy and idiopathic hypersomnia (IH); Epidiolex for seizures associated with Lennox-Gastaut syndrome (LGS), Dravet syndrome (DS), or tuberous sclerosis complex (TSC); Rylaze for the treatment of acute lymphoblastic leukemia or lymphoblastic lymphoma; Enrylaze to treat acute lymphoblastic leukemia and lymphoblastic lymphoma; Zepzelca for the treatment of metastatic small cell lung cancer with disease progression on or after platinum-based chemotherapy; Ziihera to treat HER2-positive biliary tract cancers; Modeyso for the treatment of diffuse midline glioma harboring an H3 K27M mutation; and Defitelio to treat severe veno-occlusive disease. It also develops Zanidatamab in Phase 3 trial to treat HER2-positive gastroesophageal adenocarcinoma (GEA) and biliary tract cancers (BTC); Dordaviprone to treat H3 K27M-mutant diffuse glioma; and Vyxeos for the treatment of newly-diagnosed therapy-related acute myeloid leukemia. In addition, the company is developing Zanidatamab to treat neoadjuvant and adjuvant breast cancer; Vyxeos for the treatment of High-risk MDS, newly diagnosed untreated patients with high-risk AML, and De novo intermediate or adverse risk AML stratified by genomics; and JZP3507 to treat pheochromocytoma and paraganglioma that are in Phase 2 clinical trials. Further, it develops JZP815 to treat Raf and Ras mutant tumors; JZP898 for the IFN INDUKIN molecule in solid tumors; and JZP047 to treat absence epilepsy that are in Phase 1 clinical trials. The company has licensing and collaboration agreements with Redx Pharma plc, Autifony Therapeutics Limited, Zymeworks Inc., Sumitomo Pharma Co., Ltd., and Werewolf Therapeutics, Inc. Jazz Pharmaceuticals plc was founded in 2003 and is headquartered in Dublin, Ireland.

Moat Signals

Competitive analysis based on 60 quarters of fundamental data

Pricing Power

Weak Moat

Operating margins are under pressure, averaging 6.0%. The business may lack pricing power or face rising costs.'

Competitive Advantage

Weak Moat

ROE is low or negative, suggesting limited competitive advantage or capital allocation challenges.

Cash Generation

Moderate Moat

8 of the last 8 quarters generated positive FCF. The company generally funds itself but has occasional cash consumption quarters.

Demand Durability

Strong Moat

TTM revenue has grown consistently (6 of 7 quarters up), with ~13.5% growth over the period. Strong demand durability.

Risk Signals

Data-driven red flags and warnings across 60 quarters

Some Concerns

Margin Pressure

Red Flag

Operating margins dropped 114.1% over recent quarters — a sharp decline suggesting serious cost or pricing challenges.

Earnings Quality

Healthy

FCF covers net income by 0.7x on average — earnings are well-supported by cash generation.

Leverage Risk

Healthy

D/E ratio is 1.0 — conservative capital structure with low financial risk.

Revenue Decline

Healthy

Revenue is stable or growing over recent quarters — demand appears durable.

Cash Burn

Healthy

Free cash flow is consistently positive — the business self-funds without external capital reliance.

Share Dilution

Healthy

Share count is stable — no significant dilution or buyback activity.

Metrics at a Glance

as of March 2026

Revenue & Profit

Revenue, EBITDA, operating income, net income, EPS, and shares

TTM Revenue
$4.44B
9.2%
Q. Revenue
$1.07B
TTM EBITDA
$675.08M
46.3%
TTM Op. Income
$-37.75M
106.3%
Q. Op. Income
$336.60M
TTM Net Income
$29.49M
93.9%
Q. Net Income
$293.10M
EPS
$4.73
Shares Out.
$61.90M
1.5%
$4.44B in TTM revenue grew 9.2% YoY, reaching $1.07B last quarter. TTM EBITDA of $675.08M and TTM operating income of $-37.75M shows growth is flowing through. Net income of $29.49M TTM confirms the company is converting revenue into profit. Revenue is growing at a healthy pace — a signal to hold.

Margins

Gross, EBITDA, operating, and net margin trends

EBITDA Margin
48.5%
Op. Margin
31.5%
605.9%
Net Margin
27.4%
366.0%
Op. margin of 31.5% is up 37.7% YoY — cost efficiency is improving. Net margin at 27.4%.

Price Ratios

P/E, P/S, P/B, EV/EBITDA, FCF yield, and earnings yield

P/E Ratio
511.0x
P/S Ratio
3.4x
P/B Ratio
3.3x
At 511.0x P/E, the stock trades at a premium — the market expects above-average growth. P/S of 3.4x and P/B of 3.3x provide additional context. Assess whether the current multiple is justified by the company's growth and profitability trajectory.

Assets & Liabilities

Total assets, cash, debt, book value, and leverage

Total Assets
$11.86B
Cash
$1.84B
Long-Term Debt
$4.32B
Book Value
$4.53B
D/E Ratio
1.0
Debt/EBITDA
8.3
With $11.86B in assets and $4.32B in long-term debt, the D/E of 1.0and book value of $4.53B — shows a conservative capital structure — the company has a strong financial cushion to weather downturns.

Cash Flow

Operating cash flow, free cash flow, FCF margin, and earnings quality

Op. Cash Flow
$408.20M
Free Cash Flow
$388.50M
6.6%
FCF Margin
8.8%
FCF / Net Income
1.3
FCF of $388.50M on $408.20M in operating cash flow. The FCF / Net Income ratio of 13.2x means earnings are well backed by actual cash — high-quality earnings.

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