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Neurocrine Biosciences (NBIX) Stock Fundamentals, Analysis & Risk Signals

Health score, competitive moat, risk signals, and key metrics at a glance.

NasdaqGS•Healthcare•Drug Manufacturers - Specialty & Generic
A
ExcellentMetricSide Score: 88/100
ProfitabilityProfit30/30
GrowthGrowth25/25
Balance SheetBalance17/25
Cash QualityCash16/20
Price & Volume
Market Cap $17.51B

Neurocrine Biosciences, Inc. discovers, develops, and commercialize pharmaceuticals for neurological, psychiatric, endocrine, and immunological disorders in the United States and internationally. The company's products include INGREZZA for tardive dyskinesia and chorea associated with Huntington's disease; Orilissa tablets for endometriosis; Oriahnn capsules to treat uterine fibroids; and CRENESSITY to treat congenital adrenal hyperplasia, as well as offers products under the name of ALKINDI and Efmody. Its product candidates in clinical development includes NBI-1076986 to treat movement disorders; Osavampator for inadequate response to treatment in major depressive disorder; NBI-1117568 for the treatment of schizophrenia and bipolar mania; NBI-1117567 for the treatment of Alzheimer's disease; NBI 921355 for the treatment of epilepsy; NBIP-01435 for the treatment of congenital adrenal hyperplasia; NBIP-2118 for the treatment of obesity and related metabolic diseases; and NBI-1070770 to treat major depressive disorder; and NBI-1117570, NBI-1117567, NBI-1117569, NBI-1140675, and NBI-1065890 for neuropsychiatric and neurological conditions. The company also has license and collaboration agreements with Nxera Pharma UK Limited; Takeda Pharmaceutical Company Limited; Xenon Pharmaceuticals Inc.; Voyager Therapeutics, Inc.; Sanofi S.A.; Tanabe Pharma Corporation; and AbbVie Inc. The company was incorporated in 1992 and is headquartered in San Diego, California.

Moat Signals

Competitive analysis based on 60 quarters of fundamental data

Pricing Power

Strong Moat

Operating margins are expanding at ~22.8%, suggesting durable pricing power and cost discipline.

Competitive Advantage

Moderate Moat

ROE is positive at ~14.3% on average, adequate but below the threshold typically associated with wide moats.

Cash Generation

Strong Moat

Free cash flow is consistently positive and growing — a hallmark of a capital-light business that can self-fund growth.

Demand Durability

Strong Moat

TTM revenue has grown consistently (7 of 7 quarters up), with ~46.4% growth over the period. Strong demand durability.

Risk Signals

Data-driven red flags and warnings across 60 quarters

Low Risk

Margin Pressure

Healthy

Margins are stable or improving at ~25.3% — no sign of cost or pricing stress.

Earnings Quality

Healthy

FCF covers net income by 2.0x on average — earnings are well-supported by cash generation.

Leverage Risk

Healthy

Limited debt-to-equity data available.

Revenue Decline

Healthy

Revenue is stable or growing over recent quarters — demand appears durable.

Cash Burn

Healthy

Free cash flow is consistently positive — the business self-funds without external capital reliance.

Share Dilution

Healthy

Share count is stable — no significant dilution or buyback activity.

Metrics at a Glance

as of March 2026

Revenue & Profit

Revenue, EBITDA, operating income, net income, EPS, and shares

TTM Revenue
$3.10B
28.6%
Q. Revenue
$814.50M
TTM EBITDA
$818.70M
56.4%
TTM Op. Income
$788.90M
59.4%
Q. Op. Income
$193.40M
TTM Net Income
$668.60M
118.6%
Q. Net Income
$197.90M
EPS
$1.97
Shares Out.
$100.50M
0.8%
$3.10B in TTM revenue grew 28.6% YoY, reaching $814.50M last quarter. TTM EBITDA of $818.70M and TTM operating income of $788.90M shows growth is flowing through. Net income of $668.60M TTM confirms the company is converting revenue into profit. Revenue is growing at a healthy pace — a signal to hold.

Margins

Gross, EBITDA, operating, and net margin trends

EBITDA Margin
24.6%
Op. Margin
23.7%
476.1%
Net Margin
24.3%
1661.1%
Op. margin of 23.7% is up 19.6% YoY — cost efficiency is improving. Net margin at 24.3%.

Price Ratios

P/E, P/S, P/B, EV/EBITDA, FCF yield, and earnings yield

P/E Ratio
26.2x
P/S Ratio
5.6x
P/B Ratio
5.1x
At 26.2x P/E, the stock trades in line with market averages — fairly valued. P/S of 5.6x and P/B of 5.1x provide additional context. Assess whether the current multiple is justified by the company's growth and profitability trajectory.

Assets & Liabilities

Total assets, cash, debt, book value, and leverage

Total Assets
$4.91B
Cash
$266.50M
Long-Term Debt
N/A
Book Value
$3.41B
D/E Ratio
N/A
Debt/EBITDA
0.0

Cash Flow

Operating cash flow, free cash flow, FCF margin, and earnings quality

Op. Cash Flow
$145.80M
Free Cash Flow
$136.70M
152.7%
FCF Margin
4.4%
FCF / Net Income
0.7
FCF of $136.70M on $145.80M in operating cash flow. The FCF / Net Income ratio of 0.2x indicates partial cash conversion — earnings quality needs attention.

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