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Pfizer (PFE) Stock Fundamentals, Analysis & Risk Signals

Health score, competitive moat, risk signals, and key metrics at a glance.

NYSE•Healthcare•Drug Manufacturers - General
C
AverageMetricSide Score: 50/100
ProfitabilityProfit25/30
GrowthGrowth9/25
Balance SheetBalance11/25
Cash QualityCash5/20
Price & Volume
Market Cap $138.41B

Pfizer Inc. discovers, develops, manufactures, markets, distributes, and sells biopharmaceutical products in the United States and internationally. It operates in three segments: Biopharma, PC1, and Pfizer Ignite. The company offers internal medicine products, including cardiovascular metabolic diseases products under the Eliquis brand; migraine products under the Nurtec ODT/Vydura and Zavzpret brand; vaccines under the Prevnar family, Abrysvo, Nimenrix, FSME/IMMUN-TicoVac, and Trumenba brands; and Paxlovid for the treatment of COVID-19. It also provides inflammation and immunology products, such as Xeljanz, Enbrel, Cibinqo, Litfulo, Eucrisa, and Velsipity; rare disease products for therapeutic areas comprising amyloidosis, hemophilia, and endocrine diseases under the Vyndaqel family, Genotropin, BeneFIX, Xyntha, Somavert, Ngenla, and Hympavzi brands; and anti-infective and immunoglobulin medicines under the Zavicefta, Octagam, and Panzyga brands. In addition, the company offers oncology products comprising ADCs, small molecules, bispecific, and other immunotherapies for the treatment of cancers, including breast cancer, genitourinary cancer, and hematologic malignancies, as well as melanoma, gastrointestinal, gynecological, and lung cancer under the Ibrance, Xtandi, Padcev, Adcetris, Inlyta, Lorbrena, Bosulif, Tukysa, Braftovi, Mektovi, Orgovyx, Elrexfio, Tivdak, and Talzenna brands. Further, it provides biosimilars under the Inflectra brand; oncology biosimilars comprising Retacrit, Ruxience, Zirabev, Trazimera and Nivestym, and other biosimilars; and sterile injectables, such as Sulperazon, Atgam, Fragmin, Solu Medrol, Solu Cortef, and Bicillin. The company has collaboration agreements with Bristol-Myers Squibb Company; Astellas Pharma US, Inc.; Merck KGaA; and BioNTech SE, as well as a strategic collaboration with Boltz, PBC to develop and deploy biomolecular AI foundation models. Pfizer Inc. was founded in 1849 and is headquartered in New York, New York.

Moat Signals

Competitive analysis based on 66 quarters of fundamental data

Pricing Power

Strong Moat

Operating margins are expanding at ~21.2%, suggesting durable pricing power and cost discipline.

Competitive Advantage

Weak Moat

ROE is low or negative, suggesting limited competitive advantage or capital allocation challenges.

Cash Generation

Moderate Moat

6 of the last 8 quarters generated positive FCF. The company generally funds itself but has occasional cash consumption quarters.

Demand Durability

Moderate Moat

Revenue shows resilience with 4 of 7 quarters posting growth — demand is generally stable but has seen some soft patches.

Risk Signals

Data-driven red flags and warnings across 66 quarters

Low Risk

Margin Pressure

Healthy

Margins are stable or improving at ~23.3% — no sign of cost or pricing stress.

Earnings Quality

Watch

FCF/Net Income has dropped below 0.7x in 4 quarters — monitor for earnings quality deterioration.

Leverage Risk

Healthy

D/E ratio is 0.7 — conservative capital structure with low financial risk.

Revenue Decline

Healthy

Revenue is stable or growing over recent quarters — demand appears durable.

Cash Burn

Watch

FCF turned negative in 2 of the last 8 quarters — occasional cash consumption.

Share Dilution

Healthy

Share count is stable — no significant dilution or buyback activity.

Metrics at a Glance

as of March 2026

Revenue & Profit

Revenue, EBITDA, operating income, net income, EPS, and shares

TTM Revenue
$63.31B
1.4%
Q. Revenue
$14.45B
TTM EBITDA
$21.12B
5.8%
TTM Op. Income
$14.54B
20.7%
Q. Op. Income
$4.03B
TTM Net Income
$7.49B
5.0%
Q. Net Income
$2.69B
EPS
$0.47
Shares Out.
$5.69B
0.3%
$63.31B in TTM revenue grew 1.4% YoY, reaching $14.45B last quarter. TTM EBITDA of $21.12B and TTM operating income of $14.54B shows growth is flowing through. Net income of $7.49B TTM confirms the company is converting revenue into profit. Revenue is growing modestly — monitor for acceleration or deceleration.

Margins

Gross, EBITDA, operating, and net margin trends

Gross Margin
75.4%
4.8%
EBITDA Margin
39.1%
Op. Margin
27.9%
2.3%
Net Margin
18.6%
14.0%
Op. margin of 27.9% is up 0.6% YoY — cost efficiency is improving. Net margin at 18.6% and gross margin of 75.4% — earnings take a bigger bite when COGS stays lean..

Price Ratios

P/E, P/S, P/B, EV/EBITDA, FCF yield, and earnings yield

P/E Ratio
18.5x
P/S Ratio
2.2x
P/B Ratio
1.5x
At 18.5x P/E, the stock trades in line with market averages — fairly valued. P/S of 2.2x and P/B of 1.5x provide additional context. Assess whether the current multiple is justified by the company's growth and profitability trajectory.

Assets & Liabilities

Total assets, cash, debt, book value, and leverage

Total Assets
$207.62B
Cash
$1.70B
Long-Term Debt
$60.56B
Book Value
$90.10B
D/E Ratio
0.7
Debt/EBITDA
10.7
With $207.62B in assets and $60.56B in long-term debt, the D/E of 0.7and book value of $90.10B — shows a conservative capital structure — the company has a strong financial cushion to weather downturns.

Cash Flow

Operating cash flow, free cash flow, FCF margin, and earnings quality

Op. Cash Flow
$2.62B
Free Cash Flow
$2.18B
23.0%
FCF Margin
3.4%
FCF / Net Income
0.8
FCF of $2.18B on $2.62B in operating cash flow. The FCF / Net Income ratio of 0.3x indicates partial cash conversion — earnings quality needs attention.

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